The Anaphylaxis Registry (NORA - Network for Online-Registration of Anaphylaxis) aims to collect data on severe allergic reactions. Since data collection began in 2007 across German-speaking countries, anaphylactic reactions have been continuously documented. Since 2011, NORA has been open internationally; since then, an average of around 1,300 cases per year have been recorded.
Overall, the most common triggers include insect venoms, foods, and medications—though their distribution differs between children (mainly foods) and adults (mainly insect venoms).
Anaphylaxis is a severe allergic reaction that can progress rapidly and may be fatal. An increase in anaphylactic reactions has been reported worldwide. Because anaphylactic reactions are not subject to mandatory reporting, there is no comprehensive official statistic on their frequency, course, and outcomes. In addition, modern life continually exposes people to new and sometimes unknown substances and environmental factors. Exotic foods, for example fruits, are imported from all over the world and consumed locally.
Within this project we aim to obtain information on triggers, cofactors, and treatment of patients who experienced a severe allergic reaction. Such data  will help to improve the knowledge and treatment modalities of affected patients.